Burak Ogan Mancarci

Tel: +1 778 995 1591
ogan.mancarci@msl.ubc.ca
oganm.com

Education

2013-2022

MSc, Bioinformatics; University of British Columbia (Vancouver, Canada)

Thesis title: Identification/validation of cell type marker genes of the brain and their use in estimating cell type proportions in brain samples.

2009-2013
BSc, Molecular Biology And Genetics; Bilkent University (Ankara, Turkey)

Work Experience

2022-Present
Bioinformatician - Pavlidis Lab, University of British Columbia

Research Experience

2014 - 2022

MSc Student at UBC Micheal Smith Laboratories - Supervisor: Dr. Paul Pavlidis

2013

Rotation at BC Children’s Hospital - Supervisor: Dr. Wyeth Wasserman

2013

Rotation at Simon Fraser University - Supervisor: Dr. Fiona Brinkman

2012

Summer internship at University of Zurich - Supervisor: Dr. Barbara Tschirren

2011

Summer internship at Harvard Medical School - Supervisor: Dr. George Daley

Teaching Experience

2018
Teaching Assistant for Statistical Methods for High Dimensional Biology course (STAT 540) at UBC - Instructors: Sara Mostafavi, Paul Pavlidis
2016
Teaching Assitant for Exploratory Data Analysis course (STAT 545) at UBC - Instructor: Dr. Jenny Brian
2015
Teaching Assitant for Exploratory Data Analysis course (STAT 545) at UBC - Instructor: Dr. Jenny Brian
2015
Instructional Skills Workshop at UBC - iswnetwork.ca

Publications

Lim, N., Tesar, S., Belmadani, M., Poirier-Morency, G., Mancarci, B.O., Sicherman, J., Jacobson, M., Leong, J., Tan, P. and Pavlidis, P. (2021). Curation of over 10 000 transcriptomic studies to enable data reuse. Database, 2021.

Zhuang, B., Mancarci, B.O., Toker, L. and Pavlidis, P. (2019). Mega-analysis of gene expression in mouse models of Alzheimer’s Disease. Eneuro, 6(6).

Tripathy, S.J., Toker, L., Bomkamp, C., Mancarci, B.O., Belmadani, M., and Pavlidis, P. (2018). Assessing Transcriptome Quality in Patch-Seq Datasets. Front. Mol. Neurosci. 11.

Toker, L., Mancarci, B.O., Tripathy, S., and Pavlidis, P. (2018). Transcriptomic evidence for alterations in astrocytes and parvalbumin interneurons in bipolar disorder and schizophrenia subjects. Biological Psychiatry.

Mancarci, B.O., Toker, L., Tripathy, S.J., Li, B., Rocco, B., Sibille, E., and Pavlidis, P. (2017). Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data. ENeuro 4.

Tripathy, S.J., Toker, L., Li, B., Crichlow, C.-L., Tebaykin, D., Mancarci, B.O., and Pavlidis, P. (2017). Transcriptomic correlates of neuron electrophysiological diversity. PLOS Computational Biology 13, e1005814.

Horvath, G.A., Demos, M., Shyr, C., Matthews, A., Zhang, L., Race, S., Stockler-Ipsiroglu, S., Van Allen, M.I., Mancarci, O., Toker, L., et al. (2016). Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target? Mol. Genet. Metab. 117, 42–48.

Onder, T.T., Kara, N., Cherry, A., Sinha, A.U., Zhu, N., Bernt, K.M., Cahan, P., Mancarci, B.O., Unternaehrer, J., Gupta, P.B., et al. (2012). Chromatin-modifying enzymes as modulators of reprogramming. Nature 483, 598–602.

Software

NeuroExpresso: A web application for visualization of gene expression data in brain cell types. Available at neuroexpresso.org.

markerGeneProfile: An R package for calculation of marker gene profiles as described in Mancarci et al. (2017). Available at github.com/PavlidisLab/markerGeneProfile.

VASCO: A web application for visualization of gene expression data from single cell RNA sequencing experiments. Developed for HackSeq 2016. Available at hackseq.github.io/vasco.

Viral Voyager: A web application for visualization and analysis of metavirome data collected for the Tara Oceans Project. Developed for HackSeq 2018. Available at oganm.com/shiny/taracyc.

Impact Replays: A web application for visualization play-by-play data from football games. Developed for SportsHack hackaton. Available at daattali.com/shiny/cfl.

eggstractor: Software to automate extraction of shape and pigmentation related information from quail eggs. Developed for 2012 summer internship under Barbara Tschirren. Available at github.com/oganm/eggstractor.

Misc. Bioinformatics related R packages: I maintain R packages aimed at making life easier for myslef and other bioinformaticians. See github.com/topics/ogan-bio for a full list.

Misc. D&D related repositories: I maintain R packages and web applications to be used while playing Dungeon’s and Dragons, a popular tabletop roleplaying game. See github.com/topics/ogan-dnd for a full list.